No single magic number; three to four IUI cycles are typical before reassessing The article advises couples to try about three to four good IUI cycles, after which success chances plateau and a move to IVF becomes sensible [1].
IUI is cheaper and simpler, suited for younger couples or mild infertility Because IUI is less invasive and less costly, it remains the first‑line option for patients under 35 and for cases like unexplained infertility or mild sperm issues [1][3].
Age dictates how many IUI attempts are reasonable Patients under 35 may undergo three to four stimulated IUIs; those 35‑40 are often limited to two or three cycles; over 40 or with poor ovarian reserve are advised to proceed to IVF promptly [1][4].
Certain diagnoses bypass IUI entirely, making IVF the first choice Blocked fallopian tubes, severe male factor infertility, or any condition preventing egg retrieval or sperm penetration leads clinicians to recommend IVF, often with ICSI, as the initial treatment [1].
Success rates favor IVF: IUI yields single‑digit to low‑teen per‑cycle live‑birth rates, while IVF offers higher per‑cycle odds Cohort data show IUI’s cumulative chances are modest compared with IVF’s superior per‑cycle outcomes, influencing the cost‑benefit balance [1].
Financial strain is a major concern for couples considering assisted reproduction A linked study highlights the high cost of infertility treatments and the resulting financial pressure on patients [2].