Colorectal Cancer Deaths Surge Among U.S. Adults Under 50, Screening Gap Highlighted
Updated (3 articles)
Deaths Among Under‑50s Increase 1% Annually Since 2005 A national analysis shows colorectal cancer deaths have risen about 1 % each year for people younger than 50 since 2005, and by 2023 the disease became the leading cause of cancer‑related mortality in this age group, overtaking lung, breast, and brain cancers [1].
Incidence Peaks in 20‑ and 30‑Year‑Olds, Changing Disease Profile Researchers observed a steep climb in new cases among individuals in their 20s and 30s, confirming clinicians’ reports that colorectal cancer, once rare in these decades of life, is now increasingly common [1].
Screening Guidelines Begin at 45, Leaving Younger Adults Unchecked Current average‑risk screening recommendations start at age 45, so people under that threshold are only screened if symptoms appear, often resulting in delayed diagnosis for younger patients [1].
Patient Story Shows Survival After Early Detection and Aggressive Treatment Carolyn Vasquez was diagnosed at 27 with stage 4 rectal cancer and liver metastases in 2018; after five surgeries and chemotherapy she has remained cancer‑free for five years and is now studying to become a physician assistant [1].
Researchers Suggest Diet, Microplastics, and Antibiotics as Possible Drivers Experts, including Dr. Stacey Cohen, cite dietary changes, environmental microplastics, and alterations to gut microbiota from antibiotic use as plausible contributors, though definitive causes remain unproven [1].
Community Event Scheduled March 7 to Boost Awareness The Fred Hutchinson Cancer Center will host a free colorectal cancer awareness session at the Matt Griffin YMCA on March 7 at 10 a.m., providing education during Colorectal Cancer Awareness Month [1].
Related Tickers
Timeline
1990 – Over 1.2 million Americans under age 50 die of cancer, establishing a baseline for later trends in early‑onset disease mortality[1].
Early 2000s – Incidence of colorectal cancer among adults under 50 begins climbing steadily, marking the start of the early‑onset surge noted by researchers[2].
2005 – Mortality in the under‑50 group rises about 1.1 % per year, a trend that continues for more than a decade and contrasts with declines in other cancers[1][3].
2014‑2023 – Average annual death rates fall for brain (‑0.3 %), breast (‑1.4 %), leukemia (‑2.3 %) and lung (‑5.7 %) cancers, while colorectal mortality stays flat, widening its share of under‑50 deaths[1].
2023 – Colorectal cancer overtakes lung, breast and brain cancers to become the leading cause of cancer‑related death for U.S. adults under 50, according to national mortality data[1][3].
Jan 22, 2026 – A JAMA analysis of U.S. mortality through 2023 confirms colorectal cancer as the top killer under 50 and stresses that “screening alone is not enough,” warning of a large diagnostic gap highlighted by MD Anderson’s Y. Nancy You[1].
Feb 12, 2026 – Actor James Van Der Beek dies at 48 from colorectal cancer, joining other high‑profile cases; researchers project 158,000 new cases and roughly 3,890 deaths among under‑50s this year, and Dr. John Marshall advises “eat more fruits, vegetables, whole grains and reduce meat intake” to lower risk[2].
Feb 21, 2026 – New data show a 1 % yearly rise in under‑50 colorectal cancer deaths and a steep incidence increase in 20‑ and 30‑year‑olds; Dr. Stacey Cohen notes that “patients under that age are screened only if symptoms appear,” underscoring gaps in the current 45‑year screening threshold[3].
Mar 7, 2026 – Fred Hutchinson Cancer Center holds a free community awareness session at the Matt Griffin YMCA at 10 a.m., providing education and early‑detection resources during Colorectal Cancer Awareness Month[3].
2026 onward – National guidelines recommend yearly stool‑based tests or colonoscopy every ten years for average‑risk adults beginning at age 45, and a newer blood test becomes available for those 45 and older, expanding screening options for early‑onset disease[2].
2026 onward – Ongoing research suggests three‑year exercise programs improve survival and that gut‑microbiome modulation may help explain the surge in younger patients, pointing to potential preventive strategies[2].
All related articles (3 articles)
External resources (9 links)
- https://pmc.ncbi.nlm.nih.gov/articles/PMC7423740/ (cited 1 times)
- https://www.cdc.gov/colorectal-cancer/screening/index.html (cited 1 times)
- https://colorectalcancer.org/basics/facts-and-statistics#:~:text=Colorectal%20cancer%20is%20the%20fourth%20most%20common%20cancer%20in,among%20men%20and%20women%20combined.&text=Each%20year%2C%20about%20150%2C000%20Americans%20are%20diagnosed%20with%20colorectal%20cancer.&text=More%20than%2050%2C000%20people%20will%20die%20from%20colorectal%20cancer%20this%20year.&text=One%20in%2024%20people%20will,colorectal%20cancer%20in%20their%20lifetime. (cited 1 times)
- https://faculty.mdanderson.org/profiles/yi-qian_you.html (cited 1 times)
- https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2025.25467?guestAccessKey=5eabd609-08b0-47c7-a738-916c7acdcc37&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=012226 (cited 1 times)
- https://pressroom.cancer.org/under-50-mortality-declines (cited 1 times)
- https://www.cancer.org/cancer/types/colon-rectal-cancer/detection-diagnosis-staging/signs-and-symptoms.html (cited 1 times)
- https://www.fredhutch.org/en/events/colorectal-cancer-community-awareness-event.html (cited 1 times)
- https://www.fredhutch.org/en/faculty-lab-directory/cohen-stacey.html (cited 1 times)