Disappearance Occurs Saturday Night in Catalina Foothills Nancy Guthrie, 84, vanished around 9:45 p.m. Saturday after relatives dropped her off at her home; she was reported missing Sunday when she failed to appear at church [1][2][3]. The elderly woman has limited mobility, high blood pressure, a pacemaker, and heart issues, and investigators noted signs of forced entry at the residence [1][2]. Pima County Sheriff’s Department treats the case as a likely abduction, but no suspect or person of interest has been identified despite interviews and camera‑footage review [1][3].

Family Posts Emotional Video Demanding Proof of Life Savannah Guthrie and siblings Annie and Cameron uploaded a four‑minute Instagram video on Wednesday, pleading for the public’s help and stating they are “ready to talk” with any kidnapper [3][1]. The family warned that “voices and images are easily manipulated” and insisted on undeniable evidence that Nancy is alive before negotiations [1][3]. Their appeal has drawn nationwide attention, prompting vigils and a $25,000 reward from a New York church [1].

Ransom Notes Cite Cryptocurrency, Prompt Federal Involvement The sheriff’s office confirmed receipt of alleged ransom communications demanding payment in digital currency, though details remain unverified [2][3]. FBI assistant special agent Jon Edwards confirmed the bureau is assisting local investigators and evaluating every lead [2]. President Donald Trump announced on Truth Social that he is directing “ALL Federal Law Enforcement” to support the search, effectively mobilizing nationwide resources [1][2].

Forensic Clues, Community Vigils, and Upcoming Briefing Shape Investigation Investigators collected apparent blood outside the home, DNA samples, and noted a brief loss of pacemaker telemetry early Sunday, all informing the timeline of the kidnapping [2]. A candlelight vigil at St. Philip’s in the Hills Episcopal Church attracted hundreds, while a $2,500 reward is offered for information leading to an arrest [2][1]. The sheriff’s office scheduled a follow‑up press conference for Thursday at 1 p.m. ET to update the public [2][3].